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Current Opinion in Pharmacology

Microglial dysfunction further impairs synaptic pruning, maintaining immature excitatory synapses and disrupting excitatoryinhibitory balance, a hallmark of ASD-related cognitive and behavioral deficits (Toscano et al

Nutrient deficiencies along either of the pathways may result in elevated homocysteine levels

The clinical efficacy of glutathione is also supported by large-scale patient-reported outcomes among people managing the overlapping triad of Long COVID, ME/CFS, and POTS/dysautonomia, where glutathione therapies are frequently rated among the more helpful interventions for this complex neuroimmune symptom cluster