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[16] [17] Chemistry [edit] Retatrutide is a peptide with the following amino acid sequence [18] YAQGTFTSDYSILLDKKAQAAFIEYLLEGGPSSGAPPPS where letters with superscripted numbers refer to the following chemical modifications: A 2-aminoisobutyric acid (Aib)

It works by copying the actions of a natural hormone in the body called GLP-1

A new mechanism for bile acid diarrhea: Defective feedback inhibition of bile acid biosynthesis

In immune cells, PGE2 signals through Ptger4 to modulate the functions of T lymphocytes and dendritic cells, promoting Th1 cell differentiation and enhancing IL23driven Th17 cell amplification in vitro