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Once the first dose is administered, the medication travels through the bloodstream to bind with receptors in the pancreas and the brain
On the kidneys, a pooled analysis of Phase 2 obesity and type 2 diabetes data showed reductions in the standard kidney-injury marker (the urine albumin-to-creatinine ratio, or UACR) of approximately 37% in adults with type 2 diabetes and 31.5% in adults with obesity but no type 2 diabetes, both on the 12 mg dose [12]
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