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Therapeutic Areas Peptide Therapeutics : Medications based on peptides (short chains of amino acids) designed to mimic natural processes in the body

We report that dual blockade with our fully human GDF8 and ActA blocking antibodies during GLP-1 RA-treatment of obese mice and NHPs preserves lean mass, while also increasing fat loss and improving metabolic measures

Plasma corticosterone levels of GLP-1R KD were also increased in response to acute stress, while baseline corticosterone levels were similar between GLP-1R KD and control, indicating that actions of GLP-1 may be partially by limiting acute stress-induced plasma corticosterone production

We recognize the importance of managing side effects, so your care plan may include medication to alleviate them