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Ozempic and Zepbound are popular options for weight loss management, but they work in different ways
Oral semaglutide: a review of the first oral glucagon-like peptide 1 receptor agonist
Why pulsatile and endogenous matters Because these analogs stimulate the pituitary rather than replacing GH, the resulting secretion tends to preserve the bodys natural pulsatile rhythm and remains subject to normal feedback control somatostatin, IGF-1 negative feedback, and the finite secretory capacity of the gland
The issue is these individuals have a set-point weight that the body is trying to get back to every time weight loss occurs
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