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Methods: We conducted a cross-sectional study in which outpatients with DC completed assessments of quality of life (Short-Form Liver Disease Quality of Life scale, SF-LDQOL, range 0-100, higher scores=higher QOL), symptom burden (Revised Edmonton Symptom Assessment Scale, ESAS-r), depression (Patient Health Questionnaire 9, PHQ-9) and anxiety symptoms (Hospital Anxiety and Depression Scale, HADS-A)

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Secretagogues like Ipamorelin and CJC-1295 offer a middle path