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Contributing Researchers Recognized for published work that shaped the scientific context discussed above Jesper Lau, PhD led the discovery and medicinal-chemistry work describing the once-weekly GLP-1 analogue semaglutide ( Journal of Medicinal Chemistry , 2015) [2]
Both semaglutide and tirzepatide are titrated, which means you begin them at low doses and increase until you achieve either your optimal or the maximum dose
Cross-trial comparisons are directional, not equivalent
These findings suggest that GLP-1RAs may have beneficial effects on cardiovascular outcomes and coronary artery disease progression in this population
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