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Most people start GLP-1s with no real plan and weight regain after stopping is common
Constipation is common on GLP-1 medications because gastric emptying and intestinal transit are both slowed
Application as an adjunct to IVF or other fertility treatments is conceivable, for example, as topical treatment to enhance endometrial lining or shield gametes during manipulation
If you experience any of the following, remain at your current dose for an additional 2 to 4 weeks before escalating: Nausea lasting more than 3 days after injection Vomiting more than once per week Inability to maintain adequate caloric intake (under 1,000 calories daily) Signs of dehydration despite increased fluid intake New onset of significant fatigue that interferes with daily function Slowing escalation is not failure
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