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Across SELECT, STEPlike trials, pediatric obesity studies, and ESSENCE, Wegovy demonstrates robust, durable weight loss, clinically meaningful CV risk reduction, and promising liver histologic responses, albeit with an established GIdominant tolerability profile and specific but manageable safety concerns
If that sounds familiar, mast cell activation syndrome (MCAS) could be part of the puzzle
The FDA actively warns against the use of such products and has issued alerts regarding compounded GLP-1 receptor agonist preparations that may pose health risks
American Diabetes Association Professional Practice Committee, Nuha A
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