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Elevation of 2 C in the BAT skin area following 1-week G49 treatment was found in parallel with an increase in thermogenic-related genes ( Cpt1b , Dio2, CoxIVi1, Ucp1, Th, Fgf21 ) and protein levels of UCP1 and TH in BAT (Fig
2021) Adults with obesity, with and without type 2 diabetes (T2D), who took 2.4 mg of semaglutide weekly over 68 weeks experienced a significantly higher change in mean body weight compared to those who took a placebo
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