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Weaknesses: Limited to specific applications, potential for high development costs
Those who discontinued semaglutide regained much of the lost weight, underscoring the need for ongoing treatment to maintain results
Standard mitigation strategies include eating smaller, lower-fat meals, avoiding lying down within two hours of eating, and slowing dose escalation if symptoms are severe
However, the review notes that these results, while promising, remain preliminary and require confirmation in larger outcome studies
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