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GLP-1s do not automatically solve this axis

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BPC157 has been shown to enhance vascular endothelial growth factor (VEGF) expression, activate VEGFR2AkteNOS signaling, and stimulate endothelial cell proliferation and migration in rodent models of hind limb ischemia and tendon injury, resulting in accelerated blood flow recovery and capillary formation (12,13)

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Combating strategies in DDR To address DDR-mediated therapeutic resistance, multiple strategies have been proposed that exploit vulnerabilities in DNA repair pathways (Fig

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Theriogenology 159:2027

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