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These pivots highlight a broader truth: traditional weight-loss businesses must evolve or risk complete disruption
GLP-1s work on gut hormones and slow digestion, producing the highest average weight loss of any current option, often 15 to 20 percent or more of body weight
A 2025 JAMA Psychiatry clinical trial found that adults with alcohol use disorder taking weekly semaglutide experienced significant reductions in alcohol cravings and consumption compared to placebo (source)
When treatment stops, the biological processes that contributed to weight gain can return
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