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However, a 2024 study published in Obesity recommends an evidence-based approach centered on a healthy dietary pattern that includes vegetables, fruits, whole grains, lean proteins, low-fat dairy, and healthy fats
Supplements may include a mulvitamin/mineral supplement, supplements for muscle support and certain probiotics
Oral semaglutide has been studied in PIONEER 6 (designed as a non-inferiority trials), with a mean follow-up of 1.3 years and positive results for the primary endpoint: the MACE rate was reduced by 21% but did not achieve statistically significant differences
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