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In senescent cells, FOXO4 binds and sequesters p53, preventing it from triggering apoptosisthis is how damaged cells survive despite accumulating stress

This provides strong, hypothesis-generating evidence that GLP-1s can act as a powerful adjunctive therapy, potentially improving the efficacy of standard hormonal treatments and helping more patients preserve their fertility

They are commonly used to address B12 deficiency, which can cause fatigue, brain fog, and low energy, particularly in people with absorption issues or plant-based diets

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