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Dose: 50-100mcg Frequency: 1-2 times per week initially Timing: 1-3 hours before intended bedtime Duration: 2-4 week assessment period This cautious approach allows you to gauge individual response before committing to more aggressive protocols

The authors established FOXO4-DRI as a first-in-class senolytic peptide tool for cellular senescence research, with mechanistic selectivity grounded in the elevated FOXO4-p53 interaction in senescent versus non-senescent cells

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