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These findings are supported by a critical review of the literature [49]
Semaglutide is a prescription medication utilized to control blood sugar levels in adults with type 2 diabetes and some weight-related conditions
But the gastrointestinal side effects it produces, particularly nausea, vomiting, and diarrhea, can cause dehydration severe enough to impact kidney function temporarily
By querying a gene expression signature of disease pathogenesis against the CMap dataset, one can find compounds that elicit a pattern of gene expression that is the opposite to the disease-related gene expression profile
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