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GLP-1R has been detected by reverse transcriptase-polymerase chain reaction in cardiac and vascular tissues isolated from both human and animal models [11],[31], and their mRNA transcripts were demonstrated in the human heart [32]
This is one strategy for reducing the nausea side effects which are commonly experienced with GLP-1 drugs
For individuals with conditions like pernicious anaemia, an autoimmune disorder that attacks the protein needed to absorb B12, oral supplements are often completely ineffective
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