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Importantly, comparative studies have consistently shown that semaglutide surpasses its predecessor, liraglutide, in efficacy across most protective measures, likely because of its extended half-life and more sustained receptor engagement (Zhang et al., 2018, 2019)
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Therefore, the repletion of NAD + levels using precursors can ameliorate this age-associated functional defects (Imai and Guarente, 2014), helping to reverse the pathogenic processes characteristic of neurodegenerative diseases (Zhang et al., 2016)
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