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SGLT2 Inhibitors The EMPA-REG OUTCOME and CANVAS studies have shown favourable all-cause mortality and cardiovascular outcomes.11,12 Meta-analyses of CVOTs confirmed the cardiovascular benefits.17,18 Three studies from landmark CVOTs further stratified patients according to baseline characteristics.21,22,23 The benefits of SGLT2 inhibitors were more apparent in patients with a history of HF and reduced ejection fraction.22,23 However, baseline risk was higher in this group of patients, possibly accounting for higher absolute risk reductions in cardiovascular outcomes

The injectable form is the version studied in every trial and the one that delivers the full dose reliably

Tart cherry concentrate (1 tablespoon): Reduces inflammation, improves sleep quality, and provides antioxidants

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