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For instance, the NICE guideline says that with total B12 values of over 350 ng/L,0 deficiency is unlikely
Standard Dosing: 250-500 mcg Per Day The clinical trial tested doses up to 500 mcg daily with no dose-limiting toxicities
[121] [123] Malabsorption [edit] Individuals with pernicious anemia do not have the ability to produce intrinsic factor
Its also been speculated that oral methylcobalamin or injected hydroxycobalamin may be preferable in smokers, but that hasnt been conrmed
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