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injection of GLP-1:GIP, GLP-1:GIP:Lani or vehicle, followed by tissue harvesting 7 h post treatment
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A 2021 Nature Microbiology study found that an Akkermansia protein called P9 triggers GLP-1 release from intestinal L-cells in mice by activating the ICAM-2 receptor, and the bacterium's metabolite propionate can also stimulate GLP-1
Necroptosis also induces macrophage IL-6 production, which upregulates CD47 on tumor cells, allowing immune evasion and driving liver metastasis and therapeutic resistance
Encourage daily movement, such as walking or light exercise, to support regularity
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