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They provide an estimate of equivocal dosages to minimize the risk of underdosing or overdose, maximize efficacy, and reduce GI side effects
For example, platinum (IV) prodrugs activated by intracellular GSH have demonstrated enhanced tumor selectivity and reduced systemic toxicity in clinical trials
This is not a bug in the medication
Your GP can refer you to a specialist or point you towards NIHR Be Part of Research (bepartofresearch.nihr.ac.uk), which lists current UK clinical trials
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