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Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes

Vitamin B12 injections are supplemental treatments containing cyanocobalamin, a synthetic form of vitamin B12

It is estimated that clinical trials evaluating liver-related events in patients with MASLD and compensated or decompensated cirrhosis would require a minimum recruitment of 2,886 patients with at least four years of follow-up and 1,602 patients with at least two years of follow-up, respectively

Ensuring rigorous methodology and overcoming operational challenges will be critical for meeting the study's objectives