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Recent studies have begun to validate these concerns
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While some of these conditions improved secondary to weight loss, other conditions are impacted directly by GLP-1RAs mechanism of action in the body
The expression of succinate dehydrogenase isoforms SDHC and SDHD was reduced by IC-B in ABMR while SDHA and SDHB were lowered by PEC in complex II, the second entrance into the ETC ( Figure 4E )
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