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Speichinger notes that sometimes there is a second step to the progesterone challenge, where estrogen is given first and followed by progesterone, to cause the withdrawal period
Tips for Equine Injections Consult Your Veterinarian: Before administering any injections, consult your veterinarian to ensure they are appropriate for your horse's specific needs
Metab Brain Dis, 32 (5), 1747-1754
Thats why frequency often becomes part of protocol planning
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