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Because decreases in FEV 1 could be due to either bronchoconstriction and/or mucus obstruction, it is possible that dual blockade of NK1 and NK2 receptors in asthmatics augmented mucus secretion and/or bronchoconstriction to allergen

372,373 The unique superparamagnetic nature, lower toxicity, and site-specific targeting capabilities of MNPs make them excellent nanocarriers for NADs delivery

What matters is the approach: both start low and titrate up over months

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