Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial
It's a selective NNMT inhibitor that preserves your NAD+ pool, reactivates sirtuin signaling, and suppresses fat storage all without touching your appetite
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expanded the number of RCTs (78) and found that the direction of effect for weight/BMI remained consistent, with an overall improvement in IR markers, albeit alongside an increased incidence of adverse events such as nausea, vomiting, and dizziness