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While all GLP-1s effectively reduce HbA1c levels, long-acting weekly GLP-1s like semaglutide and dulaglutide tend to be more effective in reducing fasting glucose and HbA1c levels compared to shorter-acting medications used daily
As previously explained, we have calculated composites representing affective symptoms of the HAMA and HAMD and somatic symptoms of the HAMD, HAMA, and FF scores [25]
Similarly, in participants aged 75 years and above, the fracture rates were 2.4% (17/703) for semaglutide and 0.6% (4/663) for placebo, respectively [80]
A potential explanation is that ESA may also be weakly utilized by other ACSL isoforms such as ACSL4, which is known to direct substrates into cholesterol esters 40
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