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GLP-1-induced weight loss can offset insulin-related weight gain

Excess adiposity, particularly in the context of obesity, is associated with increased mechanical load during physical activity, sleep-disordered breathing, and systemic inflammationall of which contribute to fatigue

After the February 2025 shortage resolution and April 22, 2025 enforcement deadline, each prescription requires prescriber evaluation and documented clinical rationale not just shortage status reasoning

We pay particular attention to any contraindications, such as a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2