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Standard dosing involves gradual titration to reduce side effects, while some functional clinicians use lower-dose or microdosing approaches for sensitive patients

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Erythropoietic protoporphyria (EPP): randomized phase 3 trials European Union trial (9 months, five implants): In EPP patients, afamelanotide increased painfree direct sunlight exposure (10:0015:00) with median 6.0 h per patient versus 0.8 h on placebo

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DOI:10.1111/ijd.12999 [ Links ] 27

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