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Additionally, metformin has demonstrated anti-inflammatory effects through the inhibition of IL-18 expression, which is linked to alterations in the intestinal microbiome (Lee et al., 2019)
unexpected signals noted (e.g., polycystic ovary) but not vaginal dryness as a labelled ADR
Side effects are usually mild and may include nausea or gastrointestinal discomfort, which typically subsides after the first few weeks of treatment
It has not been approved by the FDA or by Health Canada as of this writing, and the material sold for research is exactly that, a research compound
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