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The exact timeline for noticeable weight loss may differ, but the medication is intended for long-term use, and most patients experience significant weight loss as they continue with their treatment plan
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They are generally not recommended for patients with a personal or family history of medullary thyroid cancer or Multiple Endocrine Neoplasia syndrome type 2 (MEN2), those who are pregnant or breastfeeding or planning pregnancy, patients with a known allergy to the medication, severe gastroparesis or serious digestive motility disorders, active pancreatitis or significant pancreatitis history, serious gallbladder disease, certain kidney conditions, or active eating disorder concerns
This remains an active area of interest in melanocortin system research
