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Glutamine activates mTORC1 by enhancing glutaminolysis and the production of -KG, which is helpful for the GTP-loading of RagB and lysosomal translocation (Duran et al., 2012)
The redox signaling can regulate the canonical Wnt/-catenin signaling pathway by activating TCF 17,38,39 and that NTAPP impacts on the biological targets by generating the various oxidation molecules 10,11,12,30,35,40
doi:10.1016/j.vetimm.2012.04.001
Biological repair and adaptation rarely depend on a single signaling molecule, and many modern studies increasingly focus on network-level interactions rather than isolated mechanisms
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