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Pharmacological studies demonstrate that tesofensine's hypophagic (appetite-suppressing) effects are primarily mediated through indirect stimulation of 1 adrenergic receptors and dopamine D1 receptors in the hypothalamus

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So, with little previous research in this area we were keen to understand why this was the case and to find out what impact there was on the safety of patients. She added: We believe there is an opportunity for healthcare professionals to encourage patients to come to them for advice as our research showed that 72% are finding information around medication from online, closed support groups