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A subsequent pilot study (n=12) comparing oral liposomal glutathione (500 mg twice daily for 2 weeks) found increases in GSH levels in whole blood, erythrocytes, and plasma, along with reductions in 8-isoprostane (a marker of oxidative stress) (Buonocore et al., Oxid Med Cell Longev, 2016) [16]
The rabbits were randomly divided into three treatment groups of six animals each: a TCC group, a zinc oxide group, and a no-treatment control group
Cell culture studies further reveal lowered lipid peroxidation and markers of reactive oxygen species following Epithalon exposureindicating a protective effect on cellular membranes and biomolecules
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