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risk difference: 0.7% (95% confidence interval (CI): 1.2% to 0.2%)
Without carefully designed mechanistic experiments, it is difficult to determine whether the peptide acts directly within central compartments or indirectly through peripheral vascular, immune, or gut-brain signaling pathways
However, the beneficial, anti-inflammatory role of lactate contrasts with observations in human UC patients
Its stability in the digestive environment also allows it to be effective when taken orally, making it well-suited for gut-focused protocols
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