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There are no large, independent, randomized cardiovascular-outcome trials establishing clinical benefit in humans
Ikizler TA, Flakoll PJ, Parker RA, Hakim RM
They also clarified in another clinical study that supplements with glycine (1.33 mmol/kg/day) and N-acetylcysteine (0.81 mmol/kg/day) for 24 weeks corrected erythrocyte-GSH deficiency and alleviated oxidative stress and mitochondrial dysfunction in elderly individuals [110]
That broad action is probably one of the biggest reasons for its successits not targeting a single neuronal population or process. Most of the GLP-1 molecules cannot cross the bloodbrain barrier directly
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