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Notably, Zepbound, approved in late 2023, has shown the fastest growth, with sales projected to more than double from last year, reaching $11.3 billion
The fasting protocol is harder to control in the evening, which increases the risk of compromised absorption
GIP is also produced in the small intestine, and one of its primary effects is to directly stimulate insulin secretion in pancreatic islets
The risk may be particularly high in patients with underlying heart failure or kidney disease
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