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Here we investigated the effects of the GLP-1 agonist exenatide on palatability-driven feeding regulation in adult male rhesus macaques ( n = 5) using a novel operant food intake paradigm with four meal schedule conditions where two types of pellets with different palatability values were offered as meal in all combinations in two consecutive daily feeding sessions (S1 and S2)
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A nondescript everyday moment signaled that I wasnt at rock bottom anymore
DOI: Published online: December 30, 2021 1 Korea Mouse Metabolic Phenotyping Center (KMMPC), Lee Gil Ya Cancer and Diabetes Institute, Gachon University, Incheon, Korea 2 Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Korea 3 Division of Molecular Medicine, Gachon University College of Medicine, Incheon, Korea Corresponding author: Cheol Soo Choi Division of Molecular Medicine, Gachon University College of Medicine, 21 Namdongdaero 774beon-gil, Namdong-gu, Incheon 21565, Korea E-mail: [email protected] Copyright 2022 Korean Diabetes Association This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited
Adverse effects observed in clinical trials include: Gastrointestinal effects: nausea, vomiting, diarrhoea, and constipation particularly during dose escalation
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