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Lilly anticipates that orforglipron could receive approval for its first indication as early as next year, said a company spokesperson

His pediatrician didn't like the idea of interventions other than diet and exercise to help children lose weight, so Ambiyo didn't even want to bring up GLP-1s

Research published in BioScientifica confirms that GLP-1 receptors are located directly in the Ventral Tegmental Area (VTA) and the Nucleus Accumbens the parts of the brain that control wanting and craving. By dampening the dopamine hit we get from a binge, these medications can effectively decondition the brains reliance on food for pleasure

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