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The conversion from homocysteine to cystathionine by cystathionine -synthase (CBS) is described to be a key player in restoring intracellular cysteine pool as decreasing its expression increases sensitivity to ferroptosis in ovarian cancer cells upon erastin treatment ( However, other systems downstream of cystine uptake can also play an important role

Pitt B, Filippatos G, Agarwal R, Anker SD, Bakris GL, Rossing P, et al

Furthermore, given the limited sample size and the heterogeneity of the antipsychotic drugs administered, results should be interpreted with caution

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