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Description

In this work we directly compare the prototypical GLP-1RA exendin-4 with its C-terminally acylated analogue, exendin-4-C16, for their relative propensities to recruit and activate G proteins and -arrestins, endocytic and post-endocytic trafficking profiles, and interactions with model and cellular membranes

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company-reported topline results (TRANSCEND-T2D-1)

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