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Criteria for inclusion and exclusion This study incorporated only those investigations that fulfilled specific inclusion criteria: publications in the English language, studies involving subjects diagnosed with type 2 diabetes mellitus (T2D), randomized controlled trials (RCTs), interventions that compared the efficacy of SGLT-2 inhibitors or GLP-1 receptor agonists against placebo, and reports on major adverse cardiovascular events (MACE) or hospitalization for heart failure (HHF), as well as cardiovascular outcomes irrespective of baseline metformin usage

After 72 weeks, Zepbound outperformed Wegovy in both primary endpoints and all five secondary endpoints in a study involving adults with obesity or overweight, at least one weight-related health issue, and no diabetes

change in the taste of food or drink Constipation decreased appetite Diarrhea dizziness gas or burping heartburn mild abdominal pain or bloating nausea redness, itching, or swelling at the injection site tiredness vomiting weight loss Although most of the side effects listed below dont happen very often, they could lead to serious problems if you do not seek medical attention

What strategies do you recommend to reduce the risk of rebound weight gain if I stop the drug