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But it is also the finding that requires the most discipline in interpretation
Large observational cohorts, cardiovascular outcome trials, and pharmacovigilance analyses have not confirmed a clear increase in medullary thyroid carcinoma among treated patients
Appetite reduction lowers calorie intake, and lower calorie intake often reduces protein intake unless nutrition is intentionally structured
With seven additional Phase 3 readouts expected in 2026, retatrutide is emerging as a potential next-generation standard of care one that could fundamentally reshape the metabolic medicine landscape
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