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The citrate is converted to acetyl-CoA and oxaloacetate by ATP-citrate lyase (ACLY) and can now serve as a substrate for ACC
The test reveals predispositions in metabolic genetic pathways relevant to B12 processing
Jumping to the maintenance dose immediately leads to significant gastrointestinal side effects that can derail an entire protocol
Liraglutide, another GLP-1 receptor agonist with a longer track record than semaglutide, has not generated significant reports of b12 deficiency in clinical practice
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