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Furthermore, the study showed that tirzepatide correlated with a marked decrease in the levels of key indicators associated with fibrosis and hypertrophy, such as TGF- , Matrix Metalloprotieinase-9 (MMP9), Collagen Type I Alpha 1 (COLIA1) and F-box only protein 32 (FBXO32) [21]

Two to three HIIT sessions per week, lasting 15-25 minutes each, provide the metabolic stimulus without overtaxing recovery capacity

The results showed high heterogeneity of weight loss from the baseline weight between individuals even at the highest dose of tirzepatide 38.4 to 9.0 kg and mean 22.1 kg

Common adverse effects of GLP-1 medications include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation