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As with all GLP-1 therapies, there are important safety considerations: Not suitable for individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) May cause nausea, vomiting, diarrhea , especially during dose titration Monitor for signs of pancreatitis , gallbladder issues, or allergic reactions Not indicated for patients with Type 1 diabetes or those with severe gastrointestinal disorders Regular follow-ups, lab monitoring, and dose adjustments are part of the DrWell Methodology to ensure safe, effective outcomes

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Mouse lymphoma model and tumor xenografts The previously described mouse model of Burkitt lymphoma C57BL/6N-Tg(IGL-MYC)3Hm (-MYC mice) [35] was obtained from the NCI mouse repository (Strain code 01XA7), backcrossed to C57BL/6J for more than 10 generations, and maintained in heterozygosity in a C57BL/6 J background