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Description

This observation suggests a possible dominant negative effect of the SIRT2 N168A mutant, as SIRT2 dimerization is crucial for SIRT2 deacetylase activity (Yang et al, 2023)

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While short-term anti-inflammatory effects can be helpful, long-term immune regulation --- especially in patients with autoimmune conditions --- needs careful monitoring

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Neurochem Res 25: 11191124

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