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It also causes the skin to lighten by converting melanin to a lighter color and deactivating the enzyme tyrosinase, which helps produce the pigment 2
Drug interactions require careful evaluation: rapamycin has clinically significant interactions with certain antifungals, antibiotics, and other compounds
Beal 2005
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Mechanism of Action: It mimics the GLP-1 hormone , which regulates appetite and food intake, reducing hunger and calorie intake
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